Aesthetic clinic

Kneecap PRP Injection (Knee pain treatment Singapore)


The most common cause of knee pain is osteoarthritis – this condition is characterised by progressive wearing of the knee cartilage. 

PRP injection for knee pain treatment

There is no cure for knee osteoarthritis because of the low regenerative capability of the knee cartilage. Treatment tends to focus on addressing the pain, improving symptoms, and delaying the need for knee replacement surgery.

In addressing knee pain, doctors have traditionally relied on cortisone injections. However, cortisone shots have a limited healing effect and can harm the immune system.

In its place, platelet-rich plasma (PRP) injections have emerged as a stronger competitor. 

PRP is a form of regenerative medicine. Studies have shown that some types of PRP injections significantly improve low to moderate-grade knee osteoarthritis. The resulting benefit is improved physical function that continues at 3-, 6-, and 12-month follow-ups.

What is platelet-rich plasma (PRP)?

Produced in the bone marrow, platelets are a type of blood cell that aids with blood clotting. They contain proteins that are helpful in healing injuries.

Plasma, on the other hand, is the liquid component of the blood that is made up of protein and water. It provides a medium for the red and white blood cells, and platelets to circulate through your bloodstream. Similarly, plasma aids with blood clotting and are useful in healing injuries.

To obtain platelet-rich plasma, a small amount of your blood will be drawn and placed into a centrifuge. This spins your blood at different speeds, causing it to separate into different layers – one of which is the platelet-rich plasma. It is platelet-rich because this layer contains as much as three times more platelets than regular blood.

How can PRP injections help with knee pain?

Platelet-rich plasma contains voluminous amounts of bioactive proteins and growth factors, which are compounds that trigger and accelerate cell reparation and regeneration. When injected into the affected area, the platelet-rich plasma will break down and release these growth factors, which will activate the body’s healing process.

What is the procedure like? 


Before your PRP injection, you will likely need to take a break from blood-thinning medications and certain vitamins or supplements. Your doctor will advise you which exact medications.

As the preparation for PRP injections require drawing of blood, you may want to ensure you have something to eat before the procedure. This will help you avoid feeling light-headed when the treatment is administered.


After the PRP injection, you may experience an increase in pain at the treatment site for the first two weeks. Some redness and swelling may appear.

To manage this, you are recommended to apply a cold compress to the treatment site for 20 minutes every two to three hours, for the first two days after your treatment. During this period, avoid activities that may put an unnecessary stress on the treatment area and always check in with your doctor before you return to vigorous physical activities.

You are also advised to avoid non-steroidal anti-inflammatory medications, as these may neutralise the effect of the PRP treatment.

How long does it take for PRP to work for knee osteoarthritis?

The effectiveness of PRP injections depends on several factors including how severe your knee pain is and how advanced osteoarthritis in your knee has advanced, as well as your overall health condition. It could be several weeks before you feel any improvement.

For best results, you are recommended to receive two to three PRP injections about two weeks apart. 

PRP injections have proven to significantly improve pain in people with low- to moderate-grade arthritis, within 6 to 9 months. This positive effect can last about 12 to 18 months.

Does PRP really work for knees?

There are a few factors that make PRP injections a better knee pain treatment:

  • Its pain reduction effect is also double that of cortisone jabs
  • There is no known side effect because you will be using your own blood
  • It is a generally safe procedure with no risk of infection

Who is suitable for PRP injections?

Generally, anyone with mild- to moderate-grade knee osteoarthritis can consider getting PRP injections. However, you will not be eligible if you have one or more of the following conditions:

  • Abnormal platelet function
  • Anemia
  • Cancer
  • Low platelet count
  • Infection

How much do PRP injections cost in Singapore?

At BMB Aesthetics, PRP injections start from $1,000. 

PRP as part of a comprehensive treatment plan

Although PRP injections are found to be effective, they are often incorporated into a more comprehensive knee pain treatment plan. It is one element in a multi-faceted treatment plan that should include other aspects of therapy, such as medication and physiotherapy, to help you recover mobility and function in your knees.

All in all, knee pain treatment should include lifestyle changes and medicinal approaches to help achieve best results. Those dealing with knee pain are recommended to maintain a healthy weight to enhance and extend the pain reduction effect of the PRP injection.

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